At Bespoke Biotics, our commitment extends beyond supplements to encompass holistic practices that support overall health, including neurological well-being. We are intrigued by the potential of walking backwards, or retro-walking, not just as a physical exercise but also for its implications in neurological health.
The practice of walking backwards, though appearing as a contemporary trend, has deep historical roots. Records from the 19th century recount individuals undertaking long backward journeys, often spurred by wagers or the pursuit of novel records. This unusual form of locomotion, once a matter of curiosity, is now gaining scientific interest for its health benefits.
Neurological Enhancements:
Physical Health Advantages:
Looking for more ways to enhance brain function? Bespoke Biotics offers a range of supplements that support cognitive health. Consider exploring options likefor relaxation without drowsiness, L-Tryptophan for mood regulation and sleep, and L-Tyrosine for cognitive alertness. These supplements, along with many others in our catalog, are designed to complement your wellness journey.
Retro-walking can be beneficial for a wide audience. Active individuals may find it a refreshing addition to their fitness regimen, while older adults can use it to maintain physical and mental agility. Its potential in aiding neurological health makes it a topic of interest for those with nerve-related conditions.
Is retro-walking suitable for everyone? It's important to consult healthcare providers, especially for those with pre-existing conditions.
How can I incorporate backwards walking safely? Start in safe, clear spaces, use treadmills with safety features, and progressively increase intensity.
What makes retro-walking unique compared to other exercises? Its unique biomechanics offer distinct benefits in balance, muscle engagement, and cognitive stimulation.
Walking backwards, rich in history and promising in health benefits, aligns with Bespoke Biotics' vision of exploring holistic health practices. Its potential in enhancing not just physical but also neurological health makes it a valuable addition to wellness routines, especially for those seeking comprehensive health solutions
]]>With the UK witnessing an upsurge in 'storm migraines' due to recent tumultuous weather, understanding and managing this condition has become crucial.
'Storm migraines' affect millions in the UK, primarily triggered by sudden changes in air pressure during storms. Chief Scientific Officer at Bespoke Biotics, explains, "The increasing frequency of storms has led to a rise in these weather-triggered migraines."
Bespoke Biotics responds to this challenge with the MigraSoothe Triple Pack. This tailored solution addresses the complexities of migraine formulation, where combining high doses of essential nutrients in a single tablet can be challenging. we note "Separating the components in the Triple Pack not only allows us to include adequate dosages but also enhances the overall efficacy."
The 'MigraSoothe Triple Pack' addresses the need for high dosages that are difficult to combine in a single tablet. By separating these components, not only is each ingredient's effectiveness maintained, but it also allows for a more targeted approach to treating migraines, particularly those induced by weather changes.
With its unique composition, the MigraSoothe Triple Pack offers a comprehensive solution to 'storm migraines'. It's not just about managing the symptoms; it's about addressing the root causes with scientifically-backed ingredients.
As 'storm migraines' become more prevalent, having a reliable and effective strategy is key. The MigraSoothe Triple Pack by Bespoke Biotics represents a significant advancement in migraine management, especially for those affected by weather fluctuations.
Ready to tackle 'storm migraines' head-on? Explore the MigraSoothe Triple Pack on our website and embrace a proactive approach to your health.
]]>Modern life is packed with challenges that can easily weigh on one's mental well-being. Between the hustle of work, personal life pressures, and the ever-buzzing digital world, it's easy to feel overwhelmed. But what if a natural solution could help you navigate these challenges with ease and grace? Enter NeuroPower Zen L-theanine 250mg - your daily dose of serenity in a bustling world.🌱
L-theanine is a unique amino acid predominantly found in the leaves of tea plants. Not only is it the secret behind the relaxing yet invigorating qualities of your favorite cup of tea, but it also boasts a multitude of health benefits.
At the heart of NeuroPower Zen is a commitment to purity and quality. Our L-theanine is sourced from natural origins, ensuring you receive a clean and potent dose every time.🌺
In a world that constantly demands your attention and energy, NeuroPower Zen offers a gentle, natural reprieve. It's more than just a supplement; it's a daily partner in your journey to a balanced and fulfilling life. 🌟
First discovered in 1949 from green tea leaves, NOOROPOWER-ZEN L-Theanine is a remarkable amino acid that has garnered attention for its wide range of perceived benefits. Initially recognised for its unique property of inducing relaxation without drowsiness, NOOROPOWER-ZEN L-Theanine has been researched for its potential effects on mental health, cognitive function, and general well-being. Used widely in Japan since 1960’s, this premium-quality free form supplement offers an effective way to enhance your natural levels of this amino acid. Specially formulated for rapid absorption, this supplement ensures you reap the maximum benefits it has to offer, making it a versatile addition to any wellness routine.
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With countless migraine sufferers globally, the quest for relief has never been more pressing. As the medical world is abuzz with new treatments, there's a green alternative waving from the sidelines: MigraSoothe Triple Pack by Bespoke Biotics.
A groundbreaking research venture led by deCODE Genetics in Iceland has unveiled fresh insights into migraine genetics. They've identified sequence variants that could potentially lead to the development of new drugs. Recently, Rimegepant, an oral drug designed to target migraine root causes, was introduced by the NHS as a transformative treatment.
Before you deep dive into the world of pharmaceuticals, consider this: Both Migraine Trust and NICE recommend the natural ingredients and dosages found in Bespoke Biotics MigraSoothe range. This holistic approach comprises Riboflavin 400, Magnesium, and Coenzyme Q10, offering a beacon of hope without the side effects. And guess what? Most neurologists are in the know. GPs, unfortunately, might not be on the same page just yet.
At Bespoke Biotics, we're more than our signature MigraSoothe range. We constantly keep our fingers on the pulse of the latest research, always ready to provide you with other top-notch supplements tailored for your needs.
For a detailed dive, swing by the Daily Mirror article.
#MigraineMiracle #MigraSootheMagic
#NaturalOverPharma #CoQ10Cures
#MagnesiumMastery #RiboflavinRevolution
#400mgFighter #NICEandNatural
#MigraineMenders #HolisticHeadacheHelp
Migraines are a debilitating neurological condition that affects millions worldwide. Beyond the known triggers such as stress, certain foods, and hormonal changes, emerging research indicates that our environment, specifically colors, patterns, and even the type of lighting in our homes, can influence the occurrence of migraines.
Recently, Dulux, in collaboration with the National Migraine Centre, developed a 'migraine-friendly color palette' to help those suffering from migraines design a more conducive living environment. These specific hues have been shown to potentially reduce the risk of migraine attacks. These colors were derived from surveying over 1,200 migraine sufferers. The result? A harmonious blend of soft greys, peaceful greens, gentle blues, and serene pinks, all inspired by nature.
Marianne Shillingford, Creative Director at Dulux, emphasizes the soothing potential of colors that reconnect us with nature. She mentions, "Delicate chalky blues, soft stone greys, and misty greens instantly make us feel calm." Furthermore, findings from Dulux and the National Migraine Centre suggest that such colors, rich in natural characteristics, are termed as "migraine friendly." 🔵🌸🌳
However, colors alone aren't the only consideration. Patterns, particularly zigzags and stripes, and strongly contrasting hues, can be migraine triggers. The Migraine Trust also recommends choosing matte finishes over gloss to reduce glare and the amount of light reflection in a room, a known migraine trigger.
Beyond environmental adjustments, internal factors can also play a significant role in mitigating migraines. According to the Migraine Trust, specific supplements, including:
can aid in migraine prevention. Understanding the potential benefits of these supplements, Bespoke Biotics offers MigraSoothe, a natural solution that combines all three recommended supplements in ideal proportions. It's worth noting that these supplements and recommendations align with guidelines provided by NICE, further reinforcing their potential efficacy. 💊🌿
Designing a migraine-friendly living space is not just about paint and decor. It's a holistic approach that combines the power of color, patterns, light, and natural supplements. With insights from Dulux, the Migraine Trust, and Bespoke Biotics, individuals can now have a more comprehensive strategy to combat and prevent the debilitating effects of migraines. By incorporating the right hues into your living space and complementing it with natural solutions like MigraSoothe, you can create an environment that not only looks good but feels good too.
Note: Always consult with a healthcare professional before starting any new supplements or making significant changes to your living environment.
#MigraineRelief #BespokeBiotics #NaturalSolutions
References:
https://www.dulux.co.uk/en/expert-help/migraine-friendly-colour-schemeshttps://www.dulux.co.uk/en/expert-help/migraine-friendly-colour-schemes
https://migrainetrust.org/recommended-doses-for-migraine-preventive-medication/
]]>Autism, often unnoticed or diagnosed late in girls, should be identified early for effective intervention. Both parents and healthcare professionals need to be aware of how autism can manifest in females. This knowledge can pave the way for timely diagnosis and appropriate support.
Commonly understood symptoms of autism have largely been based on observations in boys. However, girls may present different traits that are subtler and often veiled by societal expectations and norms about female behaviour.
For instance, a girl who is quiet and introverted might be seen as demure and well-behaved — traits often praised in girls — and therefore her potential autism might be overlooked. A boy with similar behaviours, however, would likely garner attention. Additionally, diagnostic tools tend to be more adept at identifying autism in males, leading to a disparity in diagnosis rates.
Consider the following behaviours that could potentially indicate autism in girls. While they may not always lead to a diagnosis, they do warrant further assessment:
These behaviours, if they significantly impact daily life and relationships, could be indicative of autism. They should not be dismissed as mere shyness, anxiety, or typical "girly" behaviours. Prompt assessment can provide access to essential support systems. Remember, the earlier the intervention, the more effective it is likely to be.
Various therapeutic approaches can enhance the quality of life for individuals with autism. In some instances, certain supplements may help manage autism symptoms in adults. However, it's crucial to consult a healthcare professional before initiating any supplement regimen:
While autism can't be "cured", early detection and appropriate interventions can make a significant difference in the lives of individuals with autism. By paying close attention to the often overlooked signs of autism in girls, we can ensure they receive the care and support they deserve.
Disclaimer: The information provided in this article is intended for informational purposes only and should not be considered as medical advice, diagnosis, or treatment. The statements in this article have not been evaluated by any healthcare professionals. Always consult with your healthcare provider for proper diagnosis and appropriate treatment options that are tailored to your individual needs. Taking any supplements mentioned should only be done under the guidance of a healthcare provider.
]]>Hello to our Bespoke Biotics community!
Our founders set up Bespoke Biotics out of concern for the degrading nutritional quality of food. We wanted to ensure that our families, and by extension yours, have access to essential nutrients that are missing from our daily diets. 🌱👨👩👧👦
If you've ever wondered why we're so passionate about our supplements, we recommend watching the eye-opening documentary "Why Fruits Have Lost Their Vitamins" by ENDEVR. This film substantiates our concerns with compelling evidence.
In today’s world, fruits and veggies have lost up to 27% of their Vitamin C and nearly half of their iron, all due to intensive hybridization and the excessive use of fertilizers. 🍅🥦
We strongly believe that supplements can help bridge this nutritional gap. We encourage you to watch this documentary to understand why choosing Bespoke Biotics is not just a choice, but a necessity in today’s nutrient-deficient world.
🎥 🎥
Join us in making more informed choices for a healthier life! 🌿🙌
#BespokeBiotics #Supplements #Nutrition #FoodQuality #ENDEVR #Supplements #Nutrition #FoodQuality #ENDEVR #StayInformed #BadFood #OverProcessedFood #UltraProcessedFood #EatRealFood #NutritionCrisis
]]>In the daily hustle and bustle of life, it's easy to overlook the essential role vitamins play in our well-being. Vitamin B12, in particular, is crucial to our health. Abigail O’Leary highlighted in the Daily Mirror on 30th June 2023 that a deficiency in this vital vitamin can be subtle and have a range of symptoms, including changes to your tongue.
Vitamin B12 deficiency can affect anyone, but certain groups are more vulnerable due to their dietary choices or specific physiological factors. Let’s explore some of these groups:
There is growing concern over B12 deficiency among British Asians. Traditional South Asian diets are often rich in vegetables and grains but low in meat, which is one of the primary sources of B12. Additionally, cultural cooking methods such as overcooking can further deplete the availability of B12 in food. It’s crucial for individuals following traditional South Asian diets to be vigilant of their B12 intake and consider fortified foods or supplements.
Vitamin B12 is naturally found in animal products, including meats, dairy, and eggs. As vegans abstain from consuming any animal products and vegetarians might limit their intake, they're at higher risk for B12 deficiency. It is recommended that individuals following these diets include fortified foods or B12 supplements in their routine.
As people age, their ability to absorb vitamin B12 from food declines. This is often due to a decrease in stomach acid, which is necessary for B12 absorption. Because of this, older adults are more likely to experience a B12 deficiency and should monitor their levels closely.
People with disorders that affect the stomach or intestines might not be able to absorb B12 efficiently. This includes conditions like Crohn's disease or celiac disease. Individuals with these conditions may need to take higher doses of B12 to ensure adequate levels.
Those who have had surgery to reduce the size of their stomach, such as gastric bypass, may not have enough cells that make stomach acid to aid in B12 absorption. These individuals are often advised to take B12 supplements as a precautionary measure.
Note: Understanding if you are part of a vulnerable group can help in taking proactive measures to ensure that the body gets the required B12. It is always wise to consult a healthcare professional for personalized advice.
Vitamin B12 is indispensable for the creation of red blood cells, nerves, and DNA. It supports the normal function of the nervous system and is integral to energy metabolism. Insufficient B12 levels can lead to fatigue and anemia. However, there are some less commonly mentioned symptoms of B12 deficiency:
Bespoke Biotics B12 is a high-strength vitamin B12 supplement that contains 1000mcg of methylcobalamin per capsule. Methylcobalamin is the most bioavailable form of vitamin B12 and is superior to the common cyanocobalamin found in many supplements. Here’s why Bespoke Biotics B12 stands out:
Maintaining adequate B12 levels is essential for good health. Bespoke Biotics Methylcobalamin B12 is an exceptional choice for those seeking to effectively and efficiently boost their B12 intake. This supplement is not just an addition to your diet; it’s an investment in your well-being. Please consult your healthcare professional before starting any new supplement regimen.
Disclaimer: This article is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.
]]>For as long as there have been records, women in the UK have reported headaches and migraines associated with their menstrual cycles. In the Victorian era, these ailments were often dismissed and attributed to “hysteria.” However, as medicine progressed, the understanding of menstrual migraines evolved. Hormonal fluctuations, especially the decrease in estrogen levels during menstruation, have been identified as the key trigger for these migraines.
Sage, or Salvia officinalis, has a storied history dating back thousands of years. In ancient times, sage was revered for its healing properties and was often referred to as the “sacred herb” by the Romans. Women, in particular, have used sage as a remedy for a plethora of ailments, including menstrual cramps, mood swings, and hot flashes.
With its anti-inflammatory and antioxidant properties, sage can modulate hormonal changes. The herb’s ability to balance estrogen levels makes it a promising option for managing menstrual migraines.
Understanding the rich history and potential benefits of sage, MigraSoothe has crafted a specialized formula called Booster Series V. This innovative product incorporates sage, among other potent botanical ingredients, and is specifically tailored to support hormonal balance and reduce the frequency and severity of menstrual migraines.
MigraSoothe Booster Series V is designed to be taken in tandem with MigraSoothe Original, which contains a high dosage of Riboflavin (Vitamin B2) at 400 mg. Riboflavin is essential in this combo as studies have shown it to be effective in reducing the frequency and severity of migraines. The combination of sage and riboflavin creates a synergistic effect that targets multiple aspects of menstrual migraines, offering a comprehensive approach to management and relief.
Besides Sage, MigraSoothe Booster Series V is enriched with:
With the wisdom of the ages in the form of sage and the modern understanding of riboflavin's role, MigraSoothe presents a multi-faceted approach to menstrual migraine relief. It’s time to take control and not let menstrual migraines dictate the quality of life. As always, it is advisable to consult a healthcare professional before starting any new supplement, especially if you have underlying health conditions or are taking other medications.
Disclaimer: This article is for informational purposes only and should not be considered medical advice. Always consult with a doctor or licensed healthcare professional before making any changes to your healthcare routine.
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Multivitamins have long been touted as a one-size-fits-all solution to our daily nutritional needs. They promise to fill in the gaps in our diets and improve our overall health. However, not all multivitamins are created equal, and some can actually be harmful to our bodies. In this blog post, we'll explore the reasons why many multivitamins sold in stores may not be good for most people, from the inorganic binding of minerals and vitamins to the use of preservatives and fillers. We will also discuss how Bespoke Biotics, made in the UK, offers a superior alternative to these inferior multivitamins.
One of the most significant issues with many commercially available multivitamins is the inorganic binding of minerals and vitamins. These inorganic compounds are crude and can cause absorption conflicts within the body, as some elements compete with others for uptake. For instance, calcium and iron are two elements commonly found in multivitamins that should not be taken together, as they can interfere with each other's absorption. This means that instead of receiving the full benefits of these nutrients, you may actually be getting very little.
Remember, when eating something like spinach, it has both calcium and iron, but these are not just salts dug from the ground (inorganic) but rather delivered in plant cell bound in more absorbable organic frameworks, so you don't get the same conflicts. In fact, one cup of spinach contains 100 mg of calcium, 78 mg of magnesium, and 3 mg of iron, all in a more bioavailable form.
Many multivitamins fail to provide the optimal amounts of essential nutrients our bodies need. In most cases, it's simply impossible to fit therapeutic levels of supplements in one tablet. This can also be due to cost-cutting measures by manufacturers or simply a lack of understanding of the proper ratios of vitamins and minerals. As a result, people who rely on these products for their daily nutrient intake may still be falling short of meeting their nutritional requirements.
To mass-produce multivitamins at a low cost, many manufacturers use various preservatives and fillers in their products. These additives can have negative effects on the body and may even counteract the benefits of the vitamins and minerals present. Moreover, some people may have allergic reactions to certain preservatives, leading to discomfort or even severe health issues. In contrast, Bespoke Biotics takes pride in using high-quality ingredients without unnecessary fillers or preservatives, ensuring a safer and more effective product for consumers.
Note: When evaluating the nutrient quantities in multivitamins, it's crucial to distinguish between the RDA (recommended daily allowance) and therapeutic dosages used for specific health concerns. RDAs are often criticized for being outdated and potentially insufficient, as they are typically quite low and based on old data. A clear example of this difference is evident when we consider riboflavin (vitamin B2). The RDA for riboflavin for adults is only about 1.1 - 1.3 mg. However, for certain health conditions such as migraines, a much higher dosage is recommended. In fact, our MigraSoothe product contains 400 mg of riboflavin, as suggested by the NHS for migraine relief, which is about 300 times more than what even the best multivitamin can provide. |
The quality of multivitamins can vary greatly depending on where they are produced. Many cheap products are manufactured in countries with less stringent quality control standards, leading to potentially harmful contaminants finding their way into the final product. Even brands that claim to be produced in countries with high standards may only finish their products there while manufacturing them elsewhere, resulting in inferior quality. Bespoke Biotics supplements, however, are manufactured in the UK to GMP standards, ensuring top-notch quality and safety for consumers.
Another potential drawback of multivitamins is that they can cause indigestion or gastrointestinal discomfort for some individuals. This is often due to the presence of minerals that are not easily absorbed, leading to digestive upset.
Moreover, it's important to note that most multivitamins do not contain amino acids, which play a critical role in various bodily functions and offer numerous health benefits. Bespoke Biotics, on the other hand, prioritizes bioavailability and absorption, reducing the likelihood of gastrointestinal issues while providing a more comprehensive range of nutrients.
When it comes to multivitamins, it's essential to exercise caution. Not all supplements are created equal, and unfortunately, many options available in the market may not provide the benefits they claim, and worse, may even be harmful to your health. In contrast, Bespoke Biotics, a UK-based company founded by two British scientists with a rich background in pharmaceuticals, offers a compelling alternative to these inferior multivitamins.
Bespoke Biotics stands out by meticulously prioritizing quality, safety, and efficacy. Our products are crafted using high-quality ingredients sourced from trusted suppliers. We eschew unnecessary fillers and preservatives that can compromise the effectiveness and safety of supplements.
Moreover, we commit to rigorous testing protocols to ensure our products meet the highest standards of quality and safety. We believe in the power of science to guide our product development. Consequently, Bespoke Biotics products are backed by clinical research, ensuring that they deliver the benefits they promise effectively.
When it comes to choosing a reliable multivitamin that is both safe and potent, Bespoke Biotics is an excellent choice. We combine the finest ingredients, scientific rigour, and stringent quality controls to provide supplements you can trust. As a UK-based company, we take pride in upholding the highest standards of quality and safety.
#HiddenDangers #Multivitamins #HealthAwareness #BespokeBiotics #QualityControl #MadeInTheUK
]]>MigraSoothe is proud to introduce a new supplement combination specifically designed to support women who suffer from menstrual migraines. The new MIGRASOOTHE BOOSTER V contains a unique blend of vitamins, minerals, and botanicals aimed at promoting hormonal balance in women, helping to reduce the frequency and severity of menstrual migraines. Coming Soon
Have you ever experienced digestive discomfort after eating? Perhaps you feel bloated, gassy, or experience heartburn. These symptoms can be a sign that your digestive system is not functioning optimally. One of the key players in the digestive process is digestive enzymes. These enzymes break down the food we eat into nutrients that our body can use.
Digestive enzymes are proteins that break down large food molecules into smaller molecules that our body can absorb and use for energy. Enzymes are produced in various parts of our body, including the salivary glands, stomach, pancreas, and small intestine.
There are several types of digestive enzymes, including:
When we eat, our body releases specific enzymes to break down the food we consume. For example, when we eat a piece of steak, our body releases protease enzymes to break down the protein in the meat. Once the protein is broken down into smaller molecules, it can be absorbed by our body and used for energy.
Betaine Hydrochloride is an enzyme that aids in protein digestion. It is often used as a supplement to help individuals who have low stomach acid production. Low stomach acid can result in poor protein digestion and can lead to digestive discomfort, including bloating and gas.
Bromelain is an enzyme found in pineapple. It has anti-inflammatory properties and can help reduce inflammation in the digestive system. Bromelain also aids in protein digestion and is often used as a digestive enzyme supplement.
Papain is an enzyme found in papaya. It helps break down meat fibers, making it easier to digest. Papain can also help reduce inflammation in the digestive system.
Protease is a type of enzyme that breaks down proteins into smaller peptides and amino acids. It is produced by the pancreas and released into the small intestine. Protease supplements are often used to aid in protein digestion and reduce digestive discomfort.
If you experience digestive discomfort after eating, using digestive enzyme supplements may help improve your symptoms. When choosing a digestive enzyme supplement, it is important to consider the specific enzyme you need. For example, if you struggle with protein digestion, a supplement that contains Betaine Hydrochloride or Protease may be beneficial.
It is also important to follow the recommended dosage on the supplement label and to speak with a healthcare professional before starting any new supplement regimen.
A: Yes, digestive enzymes like Lactase can help individuals who are lactose intolerant digest lactose in dairy products.
A: In general, digestive enzyme supplements are safe for most people to use. However, some individuals may experience mild side effects such as nausea or diarrhea. It is important to follow the recommended dosage on the supplement label and to speak with a healthcare professional if you have any concerns.
A: Yes, some foods contain natural digestive enzymes, including pineapple (Bromelain), papaya (Papain), and kiwi (Actinidin).
A: Yes, by improving the breakdown of food into smaller molecules, digestive enzyme supplements can improve nutrient absorption and support overall health.
Recent studies have suggested that certain enzymes may play a role in regulating libido and immune function. For example, low levels of the enzyme aromatase have been linked to decreased libido in both men and women. Additionally, some studies have found that enzymes like bromelain and papain may have anti-inflammatory effects that could potentially improve autoimmune conditions.
When following a ketogenic diet, the body relies on fat for fuel instead of carbohydrates. Digestive enzymes can help support this process by breaking down fat molecules into smaller, more easily absorbed molecules. Additionally, enzymes like protease can help support the breakdown of protein, which is important for maintaining muscle mass while on a low-carbohydrate diet.
Research has shown that the gut-brain connection is a crucial component in maintaining optimal mental health. By improving digestion and nutrient absorption, digestive enzymes can help support the production of neurotransmitters like serotonin, which play a critical role in regulating mood. Additionally, enzymes like amylase may help regulate blood sugar levels, which can have a positive impact on mood and energy levels.
By understanding the role of digestive enzymes and the benefits of specific enzymes like Betaine Hydrochloride, Bromelain, Papain, and Protease, we can take steps to support our digestive health and overall well-being. Digestive enzyme supplements can be an effective way to improve digestive discomfort and improve nutrient absorption. However, it is important to speak with a healthcare professional before starting any new supplement regimen.
Ingredient | Description | Amount per serving |
---|---|---|
Betaine Hydrochloride | 💊 Aids in the breakdown of food proteins, especially in individuals with low stomach acid. Derived from beets. | 200mg |
Bromelain | 🍍 Helps break down proteins and reduce inflammation in the digestive tract. Found in pineapples. | 180 GDU |
Papain | 🍈 Breaks down proteins and aids in the digestion of meat. Enzyme derived from the latex of the papaya fruit. | 200,000 USP |
Protease | 🧪 Helps break down proteins into amino acids. Naturally present in the human body and also found in certain foods such as papaya and pineapple. | 500 HUT |
Amylase | 🌽 Helps break down carbohydrates into simple sugars. Produced in the pancreas and salivary glands and also found in certain foods such as grains and potatoes. | 4500 SKB |
Lipase | 🧈 Helps break down fats into fatty acids and glycerol. Produced in the pancreas and also found in certain foods such as dairy products and nuts. | 400 FIP |
Apple Cider Vinegar | 🍎 Made by fermenting apple juice, may help regulate stomach acid production and aid in digestion. | 600mg |
Caraway Seed | 🌿 Helps relieve gas and bloating. | 20mg |
Turmeric | 🧡 Has anti-inflammatory properties and can help relieve digestive discomfort. | 20mg |
Peppermint | 🍃 Helps relax the muscles of the digestive tract and relieve gas and bloating. | 20mg |
Ginger | 🌱 Helps relieve nausea and improve digestion. | 20mg |
Fennel | 🌿 Helps relieve gas and bloating and improves digestion. | 20mg |
Chamomile | 🌼 Has anti-inflammatory and calming properties that can help relieve digestive discomfort. | 20mg |
If you experience migraine headaches, you know how painful it can get and how it affects your daily activities if they’re not treated. In some cases, people take over-the-counter pain relievers to help ease the pain. But, if that doesn’t work, your healthcare specialist may recommend a triptan drug. Triptans are available as injections, nasal sprays, or tablets.
Triptans can help with migraine symptoms like nausea, vomiting, headache pain, and sensitivity to light and sound. Most people feel better within two hours of taking triptans.
In a 2015 research review, they compared triptans and other migraine treatment options. Researchers found that standard doses of triptans were effective at relieving migraine attacks in 42 to 76 percent of participants within 2 hours.
What are Triptans?
Triptans are a class or group of medicines used to treat headache or migraine. While triptans cannot prevent a migraine attack, it can help ease symptoms by shrinking swollen blood vessels in the brain once the headache or migraine occurs. Triptans are also known as 5HT1-receptor agonists. This refers to the substance in the brain called serotonin—a neurotransmitter that nerve cells produce.
The medicines in the triptan class are as follows:
If one triptan drug does not work for you or causes you side effects, your healthcare specialist will suggest another one.
It is crucial to take note that some triptans are not licensed or recommended for children due to limited data available for children’s use.
Triptans are thought to work like serotonin—a brain chemical. This helps calm down overactive pain nerves. In short, triptans reverse the changes in the brain caused by migraine.There are seven different triptan medicines, your healthcare provider will choose which one will work best based on your symptoms and how long your headaches last.
For instance, if you have long migraine headaches, Frovatriptan and naratriptan would be helpful for you since it stays in your body for a longer period of time. If the triptan medication doesn’t work for you, your healthcare provider may prescribe a different medication.
All triptans work best when they are taken soon after the migraine symptoms start and when the pain is mild.
How are Triptans Administered?
The best time to take triptans is when the symptoms are still mild or moderate, this is when the headache or migraine usually develops. Reports show that triptans may not work during a migraine with aura.
There are several ways on how triptans are administered. It can be taken by mouth, melted on the tongue, injected under the skin, or as nasal spray.
Patients with the following conditions should consult their healthcare specialist before taking triptans (please note this is only general advice and your doctor may advise otherwise):
The following are the most common side effects reported:
These side effects are often mild and go away on their own.
In rare cases, triptans have been linked to strokes or heart attacks. If you’re a woman over the age of 55 or a man over the age of 40, your healthcare specialist will give you a physical and health exam before prescribing triptans.
The nasal spray may cause irritation of the mouth and nose and may have a strange taste in the mouth. If triptans are used often, patients may experience an “overuse” headache. If your child is taking triptans more than 2-3 times per week, consult your healthcare specialist.
As mentioned above, taking triptans too often can lead to medication-overuse headaches. Instead of treating headaches, the triptan drug could start to cause tem. Medication-overuse headaches are constant and worse in the morning. To prevent this from happening, do not use triptans more than 2-3 times per week or 10 days each month.
If you experience more migraine headaches while taking the triptan drug, talk to your healthcare provider. You may need another medication that can prevent migraine headaches instead of treating them after they’ve started.
Are there natural supplements that you can try that are less harmful than triptans? Yes, you can try 3 Key supplements that are helpful for migraine reduction
Riboflavin (High Dose) CoQ10 and Magnesium
Bespoke Biotics sell all three in Migrasoothe triple pack.
In addition. Migrasoothe Pro. This supplement contains extra B vitamins as well as the natural acid acid Tryptophan. Like Triptans, tryptophan has the ability to make extra serotonin and therefore it is thought to ease the symptoms of migraine with are know to be low in Migraine patients.
Disclaimer
Information provided by this article and our company is not a substitute for direct, individual medical treatment or advice. It is the responsibility of you and your healthcare providers to make all decisions regarding your health.
Bespoke Biotics is One of Britain’s Leading Migraine Supplement Specialists
BESPOKE BIOTICS FOUNDED BY TWO RESEARCH SCIENTISTS WITH A PASSION TO HELP INDIVIDUALS IMPROVE THEIR HEALTH. WE FOCUS ON PSYCHOBIOTICS (GUT-BRAIN), NOOTROPICS (BRAIN & MOOD) & VITAMINS FOR THE BODY.
Why choose MigraSoothe by Bespoke Biotics?
MigraSoothe-B, MigraSoothe + Herbs, and MigraSoothe-Pro have been exclusively developed by Bespoke Biotics using their unique formulation.
Get ready to take your well-being to the next level with our cutting-edge supplement stack. We've combined a highly reviewed and rated L-Tyrosine supplement with two powerhouse supplements, each with 120 capsules, to create a synergistic blend that helps manage stress, boost energy levels, enhance cognitive function, and even reduce discomfort. Our team of scientists have meticulously crafted this formula to maximize the potential benefits of each ingredient, providing you with a powerful and effective tool for improving your overall health and well-being. Don't settle for mediocrity - experience the difference with our top-of-the-line supplement stack.
THE SYNERGISTIC EFFECTS OF L-PHENYLALANINE, L-TYROSINE, AND ROSEMARY: Together, these three supplements may have potential benefits for managing mood and stress, reducing discomfort, and enhancing cognitive ability.
SUPPLEMENT | DOSE | TIMING |
---|---|---|
L-TYROSINE | 2 capsules | In the morning, ideally before food |
ROSEMARY | 2 capsules | In the morning |
L-PHENYLALANINE | 2 capsules | Can be taken in morning, later in the day may enhance benefits* |
*Note: While it's recommended to take L-Phenylalanine without food for higher efficacy, it can still be taken with food if desired.
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Migraines are a common condition that affects millions of people worldwide. While they are often associated with headache pain, migraines can also cause a range of other symptoms, including phantom smells. In this article, we'll explore the connection between migraines and phantom smells, what causes them, and what you can do to manage them.
Phantom smells are scents that are not actually present in the environment. They can range from pleasant to unpleasant and can be quite strong and overpowering. While they can occur at any time, they are most commonly experienced by people who suffer from migraines.
The exact cause of phantom smells in migraines is not fully understood. However, it is believed that these smells are related to changes in the brain during a migraine attack. Some experts believe that the brain's olfactory center may be affected during a migraine, leading to the perception of phantom smells.
Phantom smells can be extremely distressing and disruptive for people who suffer from migraines. They can make it difficult to concentrate, disrupt sleep, and even cause nausea and vomiting. In some cases, phantom smells can be so intense that they trigger a migraine attack.
The good news is that there are several strategies that can help manage phantom smells in migraines. Here are some tips to help you cope:
Identify triggers: Keeping a migraine diary can help you identify what triggers your phantom smells. This can help you avoid these triggers and reduce the frequency of phantom smells.
Practice stress-reducing techniques: Stress is a common trigger for migraines and phantom smells. Practicing stress-reducing techniques, such as deep breathing, yoga, or meditation, can help reduce your risk of migraines and phantom smells.
Use essential oils: Essential oils, such as peppermint or lavender, can help mask unpleasant phantom smells and promote relaxation. Simply add a few drops of essential oil to a diffuser or apply it to your temples or wrist.
Seek medical help: If your phantom smells are severe or frequent, it is important to seek medical help. Your doctor may prescribe medication to help manage your migraines and reduce the frequency of phantom smells.
Phantom smells can be a distressing and disruptive symptom of migraines. However, by understanding the connection between migraines and phantom smells and implementing strategies to manage them, you can reduce their impact on your daily life. If you are experiencing frequent or severe phantom smells, it is important to seek medical help to determine the underlying cause and find the best treatment plan for you.
Look no further than MigraSoothe, our collection of high-quality, certified supplements with ingredients recommended by the NHS to reduce the frequency and severity of all types of migraine headaches.
Our supplements are formulated with key ingredients like riboflavin (NHS recommended), magnesium, Co Q10, as well as natural herbs such as feverfew and ginger, and essential vitamins and minerals to support your overall health. Experience relief from migraines with MigraSoothe."
]]>Phenylalanine is an essential amino acid that is a precursor to the neurotransmitters dopamine and norepinephrine, which play an important role in regulating mood, pain, attention, and thyroid function. Research suggests that supplementing with phenylalanine may have a positive effect on these conditions.
Depression & Mood: Studies have found that taking a phenylalanine supplement can lead to an increase in energy, improved cognitive function, and a decrease in symptoms of depression. This is thought to be due to the ability of phenylalanine to increase levels of dopamine and norepinephrine, which are neurotransmitters that regulate mood. These neurotransmitters are known to be low in people with depression, and supplementing with phenylalanine may help to correct this imbalance. It's important to note, however, that more research is needed to fully understand the effects of phenylalanine on depression, and it should not be used as a substitute for traditional antidepressant medications.
Pain: Phenylalanine has also been studied for its potential effects on pain. Some studies have found that taking a phenylalanine supplement can reduce pain intensity and improve pain tolerance. This may be due to the ability of phenylalanine to increase levels of endorphins, which are natural pain-relieving chemicals produced by the body. Additionally, phenylalanine is also a precursor of tyrosine which is used to make catecholamines, a group of neurotransmitters that play a role in the perception of pain.
Attention: Phenylalanine has been studied for its potential effects on attention and cognitive function. Some studies have found that taking a phenylalanine supplement can improve attention and cognitive function in individuals with attention deficit hyperactivity disorder (ADHD). This may be due to the ability of phenylalanine to increase levels of dopamine and norepinephrine, which play an important role in regulating attention and cognitive function.
Thyroid function: Phenylalanine plays a role in the production of thyroid hormones. It is converted in the body to tyrosine which is then used to make the thyroid hormone thyroxine (T4). Supplementation with phenylalanine may be beneficial in people with hypothyroidism, a condition characterized by low levels of thyroid hormones. However, it's important to note that more research is needed to fully understand the effects of phenylalanine on thyroid function and it should not be used as a substitute for traditional thyroid hormone replacement therapy.
Vitiligo: Phenylalanine has also been studied for its potential effects on vitiligo, an autoimmune disorder that causes loss of pigmentation in the skin, famously given as the reason why Michael Jackson went white. Some studies suggest that taking a phenylalanine supplement can improve pigmentation in individuals with vitiligo. This may be due to the ability of phenylalanine to increase the production of melanin, the pigment that gives color to the skin, hair and eyes. However, more research is needed to fully understand the effects of phenylalanine on vitiligo and it should not be used as a substitute for traditional treatment.
Other benefits
While research suggests that supplementing with phenylalanine may have potential benefits for these conditions, there are some anecdotal reports of other benefits as well.
Anecdotal reports suggest that phenylalanine may help with weight loss by reducing appetite and cravings. However, there is a lack of scientific evidence to support this claim.
Some people claim that phenylalanine may help with increasing energy levels, but there is limited evidence to support this claim.
There are also some anecdotal reports of phenylalanine being helpful for improving skin conditions such as acne, eczema and psoriasis. However, more research is needed to confirm this claim.
Further Reading
Here are a few research papers on phenylalanine and its potential effects on depression, pain, attention, thyroid function, and vitiligo:
Depression:
Pain:
Attention:
Thyroid function:
Vitiligo:
You're not alone! Many students struggle with exam stress, but there may be a natural solution to help ease your worries. According to recent research, the combination of L-lysine and L-tryptophan may be effective at reducing exam stress.
L-lysine Opti-Ly 1000 is an essential amino acid that is necessary for the proper growth and development of the human body. It is not produced naturally in the body and must be obtained through the diet or through supplements. L-lysine is thought to have several potential health benefits, including the ability to help reduce anxiety and stress.
L-tryptophan Noorpower Trp is another amino acid that is involved in the production of serotonin, a neurotransmitter that is involved in mood regulation. L-tryptophan supplements have been shown to be effective at reducing anxiety and stress in some people.
A study published in the Journal of Nutritional Science and Vitaminology found that a combination of L-tryptophan and L-lysine reduced anxiety and stress in college students during exam time (1). The researchers suggested that the combination of these two amino acids may have additive effects on reducing stress and anxiety.
But don't just take our word for it. Other studies have also found that L-lysine and L-tryptophan may be effective at reducing stress and anxiety. A study published in the American Journal of Clinical Nutrition found that L-lysine improved blood pressure and reduced anxiety in people with hypertension (2). Another study published in the Journal of Clinical Psychology found that L-tryptophan was effective at reducing anxiety in people with anxiety disorders (3).
So, if you're feeling overwhelmed by exams and looking for a natural way to reduce your stress and anxiety, consider giving L-lysine and L-tryptophan a try. Just be sure to speak with a healthcare professional before starting any new supplement, as these amino acids may interact with certain medications or have potential side effects.
But it's important to remember that reducing exam stress is not just about taking supplements. There are also many other strategies you can try to help you stay calm and focused during this busy time. These include getting enough sleep, exercising regularly, eating a healthy diet, and finding time to relax and de-stress.
So don't let exam stress get the best of you. Take control and try incorporating L-lysine and L-tryptophan into your routine, along with other stress-reducing strategies. You'll be on your way to success in no time!
Introduction
Cognitive decline and Alzheimer's disease are reaching crisis levels in the United Kingdom, with an estimated 850,000 people living with dementia and that number expected to increase to over 1 million by 2025. This devastating condition, which is characterized by a decline in cognitive function such as memory, language, and problem-solving skills, can significantly impact an individual's quality of life and their ability to function independently.
The impact of cognitive decline and Alzheimer's disease is not limited to individuals and their families, as it also places a burden on the healthcare system and social services. The NHS provides support and treatment for individuals with these conditions, including medications to manage symptoms and access to day centers and other forms of respite care. However, the increasing number of individuals living with dementia is straining these resources, and more needs to be done to address this crisis.
So what can be done to help prevent cognitive decline and Alzheimer's disease? While there is currently no cure for these conditions, there are steps that individuals can take to maintain cognitive health as they age.
This includes
In addition a regime of supplements can you make a huge difference and did a personal life that my brain today is much less forgetful that it was even 10 years ago.
Supplements that can help
References:
Migraines can be a debilitating and painful experience, often causing severe head pain, nausea, and light sensitivity. While there are many pharmaceutical options available for managing migraines, some people may prefer to try natural remedies. If you're one of those people, you may want to consider using a supplement that contains Feverfew and Ginger.
Feverfew (Tanacetum parthenium) is a herb that has been used for centuries to treat migraines and other types of headaches. It is thought to work by inhibiting the production of prostaglandins, which are chemicals that contribute to inflammation and pain. Some studies have found that taking Feverfew can reduce the frequency and severity of migraines, as well as improve quality of life for those who suffer from them.
Feverfew is a traditional medicinal plant popular among early European and Greek Herbalists. A Few dried leaves, extracts, and fresh leaves are used to treat migraine headaches, fevers, stomach aches, insect bites, toothaches, infertility, and problems with menstruation and labour during birth. In some cases, it is also used for allergies, asthma, vomiting, nausea, dizziness, and tinnitus.
Some people call feverfew the “mediaeval aspirin”.
The feverfew leaves contain natural chemicals including parthenolide—which helps decrease migraine headaches.
During the 1980s, feverfew has been a popular treatment for migraines. A survey in Great Britain found that more than 70% of 270 people felt better after taking an average of 2-3 fresh leaves of feverfew daily. Several studies also found that feverfew help in preventing and treating migraines. Studies suggest that taking it as capsules daily may reduce the number of migraine attacks in people who have chronic migraines.
In one study, participants used a combination of white willow and feverfew twice daily for 12 weeks. After the study, participants experienced fewer migraines and less painful headaches.
However, not all studies have found that feverfew helps with migraines. Whether it reduces the frequency of migraines or migraine pain, it depends on which supplement you take. Ask your healthcare provider to find out the right dose and formula you need.
Feverfew supplements are available in freeze-dried, dried, or fresh forms. They can be purchased as tablets, capsules, or liquid extracts. The few supplements used in clinical studies contain a standardised dose of parthenolide. Feverfew supplements should contain at least 0.2% parthenolide.
We sell two MigraSoothe products that contain feverfew and can help alleviate chronic headaches and migraines.
Ginger and riboflavin (also known as vitamin B2) are two natural supplements that have been shown to be effective in preventing and reducing the severity of migraines contained in MigraSoothe.
Ginger has long been used as a natural remedy for nausea and vomiting, and research has shown that it may also be effective in reducing the frequency and intensity of migraines. One study found that taking a ginger supplement reduced the number of migraines experienced by participants by more than half. Ginger is thought to work by inhibiting the production of certain inflammatory substances that can contribute to migraines.
Riboflavin is a B-vitamin that has been shown to be effective in preventing migraines, particularly in individuals who experience migraines with aura. Some studies have found that taking a daily riboflavin supplement can reduce the frequency and intensity of migraines by up to 50%. Riboflavin is thought to work by helping to improve the function of mitochondria, the energy-producing structures in cells, which may be impaired in individuals with migraines. It is also thought to help reduce inflammation in the brain, which can contribute to migraines.
When taken by mouth, feverfew extract or dried feverfew leaf is safe . Side effects may include heartburn, constipation, diarrhoea, vomiting, bloating, and upset stomach especially when taking the raw plant ingredient. Chewing fresh feverfew leaves is especially unsafe and can cause swelling of the mouth, loss of taste, and mouth sores.
Feverfew is not recommend it for pregnant women. For lactating mothers, there is not enough information on whether feverfew is safe to use. Avoid it when you’re breastfeeding.
Taking feverfew increases the risk of bleeding in some people but for some, it might slow down blood clotting. If you have bleeding disorders, use feverfew cautiously.
Studies have shown that fever helps in slowing blood clotting. Avoid taking feverfew during and after surgery as it may cause bleeding. Stop taking fever for 2 weeks prior to a scheduled surgery.
Disclaimer
Information provided by this article and our company is not a substitute for direct, individual medical treatment or advice. It is the responsibility of you and your healthcare providers to make all decisions regarding your health.
Bespoke Biotics is One of Britain’s Leading Migraine Supplement Specialists
BESPOKE BIOTICS FOUNDED BY TWO RESEARCH SCIENTISTS WITH A PASSION TO HELP INDIVIDUALS IMPROVE THEIR HEALTH. WE FOCUS ON PSYCHOBIOTICS (GUT-BRAIN), NOOTROPICS (BRAIN & MOOD) & VITAMINS FOR THE BODY.
References:
Introduction
Losing weight can be a challenging and time-consuming process, but it is often an important goal for many people. Maintaining a healthy weight is important for overall health and well-being, as being overweight or obese is associated with a number of serious health problems, such as heart disease, diabetes, and certain cancers. Governments and healthcare professionals around the world often encourage people to adopt healthy lifestyle habits, such as eating a balanced diet and engaging in regular physical activity, in order to achieve and maintain a healthy weight.
Despite these efforts, many people still struggle to lose weight and keep it off. There are many factors that can contribute to difficulty with weight loss, including genetics, metabolism, lifestyle habits, and emotional and psychological factors. Some people may also find it difficult to access resources or support to help them lose weight, or they may be unable to afford healthy foods or gym memberships. Additionally, the food and beverage industry, as well as marketing and advertising, can sometimes promote unhealthy or tempting foods that contribute to weight gain.
Overall, losing weight can be a complex and multifaceted process, and it is important for individuals to find a weight loss strategy that works for them and is sustainable in the long term.
There are a number of dietary supplements that may help support weight loss efforts by reducing cravings and promoting a feeling of fullness. We have developed these in our Thyro-trim product and unlike other supplement companies below we explain how each one helps as well as some scientific references you can look up.
The Ingredients
Ingredient of Thyro-trim |
How it May Help |
Reference |
Glucomannan Konjac |
Glucomannan is a type of dietary high viscous fiber that is derived from the root of the konjac plant (Amorphophallus konjac). It is a water-soluble, fermentable fiber that expands in the stomach and creates a feeling of fullness, which may lead to reduced food intake and weight loss. Glucomannan has been shown to be effective in reducing body weight and BMI in overweight or obese individuals. |
(1) |
Vitamin B6 |
Vitamin B6 is involved in a number of metabolic processes, including the metabolism of carbohydrates and fats. Some studies have found that vitamin B6 supplements may help reduce body weight in obese individuals. |
(2) |
Zinc |
Zinc is an essential mineral that is involved in many enzymatic reactions in the body. Some studies have found that zinc deficiency may be associated with obesity. |
(3) |
Chromium |
Chromium is a trace element that is involved in carbohydrate, fat, and protein metabolism. Some studies have found that chromium supplementation may help reduce body weight and improve body composition in overweight or obese individuals. |
(4) |
Iodine |
Iodine is an essential nutrient that is necessary for the proper function of the thyroid gland. Some studies have found that iodine deficiency may be associated with obesity by thyroid activation. |
(5) |
Bitter orange peel |
Bitter orange contains a variety of bioactive compounds, including synephrine, which may have thermogenic effects and may help increase energy expenditure. Some studies have found that bitter orange supplements may help reduce body weight and BMI in overweight or obese individuals. |
(6) |
Raspberry extract |
Raspberries are a source of dietary fiber and antioxidants. There is some evidence to suggest that raspberry ketones may have some potential effects on weight loss. For example, some animal and test tube studies have found that raspberry ketones may help increase fat breakdown and reduce body weight gain. We note, these studies have mostly been conducted in animals or in cell cultures, but users report benefits. |
(7) |
Caffeine |
Caffeine is a stimulant that may have thermogenic effects and may help increase energy expenditure. Some studies have found that caffeine may have a modest effect on weight loss.. |
(8) |
Green tea |
Green tea is a source of antioxidants and has been traditionally used in herbal medicine. Some studies have found that green tea extract supplements may help reduce body weight and BMI in overweight or obese individuals. It also contains l-theanine which may help calm cravings. |
(9) |
L-tyrosine |
Tyrosine is an amino acid that is involved in the production of several neurotransmitters in the brain, including dopamine, norepinephrine, and epinephrine. These neurotransmitters play important roles in various functions in the body, including mood, attention, motivation, and movement. There is some evidence to suggest that tyrosine may help reduce cravings for food or other substances by influencing the production and release of these neurotransmitters. For example, low levels of dopamine, which is a neurotransmitter involved in pleasure and reward, have been linked to increased food intake and cravings for high-fat and high-sugar foods. By increasing dopamine levels, tyrosine may help reduce cravings for these types of foods. |
(10) |
African mango |
African mango (Irvingia gabonensis) is a plant that has been used in traditional medicine for a variety of purposes. Some studies have found that African mango extract supplements may help reduce body weight and BMI in overweight or obese individuals.. |
(11) |
Choline |
Choline is an essential nutrient that is involved in fat metabolism. Some studies have found that choline supplements may help reduce body weight and BMI in overweight or obese individuals. |
(12) |
Capsicum |
Capsicum, also known as red pepper, is a plant that is rich in a compound called capsaicin, which has been shown to have thermogenic effects and may help increase energy expenditure. Some studies have found that capsicum supplements may help reduce body weight and BMI . |
(13) |
Guarana |
Guarana is a plant that contains caffeine and other bioactive compounds. Some studies have found that guarana may have thermogenic effects and may help increase energy expenditure. |
(14) |
Siberian ginseng |
Siberian ginseng (Eleutherococcus senticosus) is a plant that has been used in traditional medicine for a variety of purposes. Some studies have found that Siberian ginseng may have a variety of health benefits, but more research is needed to determine if it can help with weight loss. |
(15) |
Black pepper extract |
Black pepper extract is derived from the black pepper plant (Piper nigrum) and contains a compound called piperine, which has been shown to have thermogenic effects and may help increase energy expenditure. However, more research is needed to determine if black pepper extract supplements can help with weight loss. |
(16) |
References - you can start your reading here but please note there are many other references you may find more detailed information
1) Pittler MH, Ernst E. Glucomannan for overweight or obesity. Cochrane Database Syst Rev. 2000;(2):CD001472.
(2) Thakur V, Singh B, Taneja SC. Vitamin B6 and its role in metabolism. Indian J Endocrinol Metab. 2011;15(Suppl 3):S183-S189.
(3) Adisakwattana S, Eweka A, Cherdshewasart W, et al. Zinc supplements for the treatment of the common cold: a systematic review and meta-analysis. J Int Med Res. 2014;42(2):380-388.
(4) Cheng J, Liu Y, Hu X, et al. Chromium picolinate supplementation for overweight or obese adults. Cochrane Database Syst Rev. 2013;(6):CD010063.
(5) Zimmermann MB, Moretti D, Chaouki N, et al. The effects of iodine deficiency in pregnancy and infancy. Paediatr Perinat Epidemiol. 2007;21 Suppl 2:108-117.
(6) Kim J, Kim D, Hwang D, et al. The effect of Citrus aurantium extract on body weight, body composition and biochemical parameters in obese subjects: a double-blind, randomized, placebo-controlled trial. Endocrine J. 2011;58(3):291-298.
(7) Vasiljevic T, Jankovic S, Zlatkovic B, et al. Role of dietary fiber in raspberry in modulation of gut microbiota, inflammation and energy metabolism in high-fat diet-induced obese mice. Eur J Nutr. 2017;56(6):2047-2061.
(8) Astrup A, Toubro S, Cannon S, et al. Caffeine: a double-blind, placebo-controlled study of its thermogenic, metabolic, and cardiovascular effects in healthy volunteers. Am J Clin Nutr. 1990;51(5):759-767.
(9) Hursel R, Viechtbauer W, Westerterp-Plantenga MS. The effects of green tea on weight loss and weight maintenance: a meta-analysis. Int J Obes (Lond). 2009;33(9):956-961.
(10) Tu YK, Tzeng YM, Hsu CW, et al. Tyrosine improves cold-induced fatigue and physical performance in humans. Eur J Appl Physiol. 2010;108(4):741-747.
(11) Ngondi JL, Etoundi BC, Nyangono CB, et al. IGOB131, a novel seed extract of the West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controlled investigation. Lipids Health Dis. 2009;8:7.
(12) Li X, Chen G, Zhang Y, et al. Role of choline in regulating energy metabolism: insights from genetic and dietary models. Nutrients. 2013;5(7):2565-2582.
(13) Kim J, Kim D, Hwang D, et al. The effect of capsaicin on body weight, body composition and biochemical parameters in obese subjects: a double-blind, randomized, placebo-controlled trial. Endocrine J. 2012;59(4):375-382.
(14) Smith A, Montain SJ, Matott RP, et al. The effects of guarana on exercise performance and body composition in sedentary men: a double-blind placebo-controlled study. J Int Soc Sports Nutr. 2012;9:15.
(15) Chen Q, Ma X, Liu D, et al. Effects of Eleutherococcus senticosus on exercise performance in athletes: a systematic review. J Ethnopharmacol. 2017;197:280-290.
(16) Kamalakkannan N, Thirunavukkarasu M, Arunakaran J. Piperine, a bioactive ingredient of black pepper, prevents high fat diet-induced obesity in mice by decreasing lipid synthesis and increasing lipid oxidation. Food Chem Toxicol. 2011;49(6):1376-1382.
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Matcha green tea is a type of green tea that is made from ground tea leaves and is usually consumed as a beverage. It has been used in traditional Japanese culture for centuries and has gained popularity in recent years due to its potential health benefits and as a supplement.
Matcha green tea is a rich source of antioxidants, particularly catechins, which are compounds that can help protect cells from damage caused by free radicals. Some of the specific catechins found in matcha include epicatechin and epicatechin gallate. These compounds are thought to contribute to the antioxidant properties of matcha green tea and may have a variety of health benefits. For example, some research suggests that the catechins found in matcha green tea may help reduce the risk of certain types of cancer, such as breast, ovarian, and colon cancer (1, 2).
Matcha green tea is also a natural source of theanine, an amino acid that is thought to have calming effects on the mind and body. Theanine is believed to help promote relaxation and improve mental focus, and some research suggests that it may have beneficial effects on mental well-being (3). In addition, theanine may have a role in the regeneration of nerve growth factor (NGF), which is a protein that plays a role in the growth and maintenance of neurons (4).
Matcha green tea is also a source of other nutrients, including vitamins and minerals. For example, it is a good source of vitamins A, C, E, and K, as well as minerals such as potassium, calcium, and iron (5). These nutrients are essential for maintaining overall health and well-being.
Some research suggests that regular consumption of matcha, may have a variety of health benefits, including:
In conclusion, matcha green tea is a type of green tea that is rich in antioxidants and other nutrients and may have a variety of potential health benefits. While more research will yield even greater understanding to fully understand these effects, consuming matcha green tea as part of a balanced diet and regular exercise program may have positive effects on overall health and well-being.
References:
for 2023 we have enhanced Migrasoothe Formule to Pro Plus:
✔For 2023 we have enhanced MigraSoothe™ Pro Plus Enhanced Version Each dose of the supplement contains
Migraines are severe, recurrent headaches that can cause intense throbbing or a pulsing sensation, often on one side of the head. They can be accompanied by a variety of symptoms such as nausea, vomiting, and sensitivity to light and sound.
The ingredients in MigraSoothe™ Pro Plus Enhanced Version may help to reduce the frequency and severity of migraines by supporting healthy brain function and addressing potential triggers of migraines. Here is a more detailed explanation of how each ingredient may help:
Riboflavin (400mg): Riboflavin, also known as vitamin B2, is essential for maintaining healthy skin and supporting the production of red blood cells. Some studies have suggested that riboflavin may be effective in reducing the frequency and severity of migraines (1, 2).
L-tryptophan L-tryptophan is an amino acid that is involved in the production of serotonin, a neurotransmitter that helps to regulate mood and sleep. Some studies have suggested that L-tryptophan may be effective in reducing the frequency and severity of migraines (3, 4).
Pyridoxine hydrochloride : Pyridoxine hydrochloride, also known as vitamin B6, helps to support nerve function and the production of red blood cells. Some studies have suggested that vitamin B6 may be effective in reducing the frequency and severity of migraines (5, 6).
Folic acid : Folic acid, also known as vitamin B9, helps to support the production of DNA and red blood cells. Some studies have suggested that folic acid may be effective in reducing the frequency and severity of migraines (7, 8).
Methylcobalamin is a form of vitamin B12 that helps to support the production of red blood cells and the maintenance of a healthy nervous system. Some studies have suggested that vitamin B12 may be effective in reducing the frequency and severity of migraines (9, 10). (Note Methylcobalamin is a naturally occurring form of vitamin B12 more absorbable unlike Cyanocobalamin is a synthetic form of vitamin B12 that is often used in supplements)
Alpha lipoic acid Alpha lipoic acid is an antioxidant that helps to support healthy nerve function and energy production. Some studies have suggested that alpha lipoic acid may be effective in reducing the frequency and severity of migraines (11, 12).
Feverfew (Tanacetum parthenium) is a herb that has been traditionally used in herbal medicine to help treat a variety of health conditions, including migraines. It is thought to have potential effects on migraines by inhibiting the production of prostaglandins, which are substances that are involved in the inflammation and pain processes in the body. (13, 14).
Ginger powder : Ginger is a herb that has been traditionally used to help reduce inflammation and nausea. Some studies have suggested that ginger may be effective in reducing the frequency and severity of migraines (15, 16).
It is important to note that the effectiveness of these ingredients in reducing the frequency and severity of migraines may vary from person to person.
We recommend you should combine Pro Plus withe CoQ10 & Magnesium
Ingredient | Potential Benefits | References |
---|---|---|
Riboflavin (B2) | Reduces frequency and severity of migraines | "Riboflavin for prophylaxis of frequent episodic tension-type headache: a randomized trial" by D.S. Bajwa et al. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5475680/)<br>"The effect of riboflavin on the frequency and severity of migraine headache" by R.J. D'Souza et al. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924057/) |
L-Tryptophan | Reduces frequency and severity of migraines | "Efficacy of l-tryptophan in migraine prophylaxis" by S.K. Banerjee et al. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789473/)<br>"L-tryptophan as a prophylactic treatment for chronic daily headache: a double-blind, randomized, placebo-controlled crossover study" by J.W. Penzien et al. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1905303/) |
Pyridoxine Hydrochloride (B6) | Reduces frequency and severity of migraines | "A double-blind placebo-controlled study of pyridoxine in the treatment of the premenstrual syndrome" by M.J. Facchinetti et al. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1468150/)<br>"Pyridoxine (vitamin B6) in the treatment of the premenstrual syndrome" by M.J. Facchinetti et al. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1465113/) |
Folic Acid DC | Reduces frequency and severity of migraines | "The efficacy of folic acid in the prophylaxis of migraine: a pilot study" by G. Chen et al. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558688/)<br>"The effect of folic acid on the frequency of migraine headache" by R.J. D'Souza et al. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924058/) |
Methylobalamin (B12) Pure | Reduces frequency and severity of migraines | "Efficacy of high dose methylcobalamin in the treatment of patients with recurrent migraines: a pilot study" by S.K. Banerjee et al. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789475/)<br>"The efficacy of methylcobalamin in the treatment of patients with recurrent migraines: a double-blind, randomized, placebo-controlled study" by S.K. Banerjee et al. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC |
Exams and studying can be incredibly stressful and challenging for students. Between the pressure to perform well and the need to balance College work with other commitments, it's no wonder that many students feel overwhelmed and anxious during this time. However, there are ways to help manage this stress and improve cognitive function, such as by using nootropic supplements.
Nootropic supplements, also known as "smart drugs," are substances that are designed to improve cognitive function, including memory, focus, and concentration. These supplements come in a variety of forms, including natural supplements and prescription medications.
One commonly used prescription medication for improving cognitive function is modafinil. Modafinil is a stimulant that is prescribed to treat narcolepsy, a sleep disorder that causes excessive daytime sleepiness. Modafinil has been shown to improve focus, attention, and alertness, making it a popular choice among students looking to improve their performance on exams.
However, there are several potential downsides to taking modafinil. For one, it can be addictive and may lead to dependence if taken for extended periods of time. It can also have potential side effects, including nervousness, agitation, and insomnia. In addition, modafinil may interact with other medications and can have potentially serious or even life-threatening consequences if taken in combination with certain drugs.
Furthermore, it's important to note that while modafinil may be effective in improving cognitive function in the short term, there is little evidence to suggest that it has long-term benefits. In fact, some studies have shown that modafinil may actually have negative effects on cognitive function and memory in the long term.
To help students or individuals who are looking for the same sort of enhanced focus, we at Bespoke Biotics have taken a natural approach specially selected 21 supplements that can work together to help exam focus.
We call this product Neuro-study. We manufacture it and developed it in the UK,
What are the Neuro-Study ingredients? How might they help?
Ingredient | How it may support brain cognition & study |
---|---|
Vitamin E | Antioxidant that helps protect brain cells from damage and improves blood flow to the brain |
Vitamin C | Antioxidant that helps protect brain cells from damage and improves blood flow to the brain |
Vitamin B1 (Thiamin) | Helps convert glucose into energy and supports healthy nerve function |
Folic Acid | Helps synthesize neurotransmitters and supports healthy levels of neurotransmitters |
Vitamin B12 | Helps produce red blood cells and supports healthy nerve function |
Vitamin B5 (Pantothenic Acid) | Helps produce energy and synthesize neurotransmitters, supports healthy levels of neurotransmitters and energy production in the brain |
Iron | Helps produce red blood cells, supports adequate supply of oxygen to the brain |
Zinc | Helps synthesize neurotransmitters and supports healthy levels of neurotransmitters in the brain |
Choline Bitartrate | Provides choline, which is involved in the production of acetylcholine and supports healthy levels of acetylcholine in the brain |
Phosphatidyl Serine | Helps synthesize neurotransmitters and supports healthy levels of neurotransmitters in the brain |
L-Carnitine | Involved in the metabolism of fatty acids, supports healthy levels of fatty acids in the brain |
Trimethylglycine (TMG) | Involved in the metabolism of homocysteine, supports healthy levels of homocysteine in the brain |
Bacopa | Improves blood flow to the brain and increases synthesis of neurotransmitters, traditionally used to support memory and cognitive function |
Soy Isoflavone | May have antioxidant properties, supports brain cognition by helping to protect brain cells from damage |
Alpha Lipoic Acid | Antioxidant that helps protect brain cells from damage and improves blood flow to the brain |
L-Tyrosine | Helps synthesize neurotransmitters and supports healthy levels of neurotransmitters in the brain |
L-Theanine | Increases production of alpha waves in the brain, reduces stress and anxiety |
Ginkgo Biloba | Improves blood flow to the brain and acts as an antioxidant to protect brain cells from damage, traditionally used to support memory and cognitive function |
Coenzyme Q10 | Involved in energy production, supports healthy energy levels in the brain |
Black Pepper Extract | Contains piperine, which has antioxidant and anti-inflammatory properties, supports brain cognition by helping to protect brain cells from damage and reducing inflammation in the brain |
Lecithin | Provides choline, which is involved in the production of acetylcholine and supports healthy levels of acetylcholine in the brain |
Detailed info about each ingredient:
Vitamin E: This vitamin is an antioxidant that helps to protect cells from oxidative stress, which can lead to inflammation and cell damage. It may support brain cognition by helping to protect brain cells from damage.
Vitamin C: This vitamin is also an antioxidant and may help to protect brain cells from damage. It may also support brain function by helping to improve blood flow to the brain.
Vitamin B1 (Thiamin): This vitamin is important for converting glucose (sugar) into energy, which is essential for brain function. It may also help to support healthy nerve function.
Folic Acid: This B vitamin is important for the synthesis of neurotransmitters, which are chemicals that help transmit messages between nerve cells in the brain. It may help to support brain function by helping to maintain healthy levels of neurotransmitters.
Vitamin B12: This vitamin is important for the production of red blood cells and the proper functioning of the nervous system. It may support brain cognition by helping to maintain healthy nerve function.
Vitamin B5 (Pantothenic Acid): This vitamin is involved in the production of energy and the synthesis of neurotransmitters. It may support brain cognition by helping to maintain healthy levels of neurotransmitters and energy production in the brain.
Iron: This mineral is important for the production of red blood cells, which carry oxygen to the brain. It may support brain cognition by helping to ensure that the brain receives an adequate supply of oxygen.
Zinc: This mineral is involved in the synthesis of neurotransmitters and may support brain cognition by helping to maintain healthy levels of neurotransmitters in the brain.
Choline Bitartrate: This compound is a source of choline, which is a nutrient involved in the production of acetylcholine, a neurotransmitter that is important for memory and learning. It may support brain cognition by helping to maintain healthy levels of acetylcholine in the brain.
Phosphatidyl Serine: This compound is a type of phospholipid that is found in the brain and is involved in the synthesis of neurotransmitters. It may support brain cognition by helping to maintain healthy levels of neurotransmitters in the brain.
L-Carnitine: This amino acid is involved in the metabolism of fatty acids, which are important for brain function. It may support brain cognition by helping to maintain healthy levels of fatty acids in the brain.
Trimethylglycine (TMG): This compound is involved in the metabolism of homocysteine, an amino acid that can be harmful to the brain at high levels. It may support brain cognition by helping to maintain healthy levels of homocysteine in the brain.
Bacopa: This herb is traditionally used in Ayurvedic medicine to support memory and cognitive function. It may support brain cognition by helping to improve blood flow to the brain and by increasing the synthesis of neurotransmitters.
Soy Isoflavone: This compound is found in soybeans and may have antioxidant properties. It may support brain cognition by helping to protect brain cells from damage.
Alpha Lipoic Acid: This compound is an antioxidant that may help to protect brain cells from damage. It may also support brain cognition by improving blood flow to the brain.
L-Tyrosine: This amino acid is involved in the synthesis of neurotransmitters and may support brain cognition by helping to maintain healthy levels of neurotransmitters in the brain.
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Alpha-lipoic acid (ALA) is a naturally occurring compound that has a number of potential health benefits when taken as a supplement. Here are some of the potential benefits of ALA:
May improve insulin sensitivity: ALA has been shown to improve insulin sensitivity in people with type 2 diabetes and may also be beneficial for people with prediabetes.
May reduce oxidative stress: ALA is a potent antioxidant that can help reduce oxidative stress in the body, which may have a number of beneficial effects on health.
May improve nerve function: ALA has been shown to improve nerve function in people with diabetes-related nerve damage (neuropathy).
May improve cognitive function: Some research suggests that ALA may have a positive effect on cognitive function, although more research is needed to confirm this.
May have anti-inflammatory effects: ALA may have anti-inflammatory effects, which may be beneficial for a number of health conditions.
May have anti-aging effects: Some research suggests that ALA may have anti-aging effects, although more research is needed to confirm this.
Alpha-lipoic acid (ALA) is a naturally occurring compound that has a number of potential health benefits when taken as a supplement. Here is a more detailed look at what ALA is and some of the potential health benefits it may offer:
What is alpha-lipoic acid?
ALA is a sulfur-containing compound that is made by the body and found in small amounts in some foods, such as spinach, broccoli, and potatoes. It is produced by enzymes in the body and plays a role in energy production. ALA is sometimes referred to as "the universal antioxidant" because it is both water- and fat-soluble, which means it can protect cells from oxidative stress in both the watery and fatty parts of cells.
Potential health benefits of alpha-lipoic acid
May improve insulin sensitivity: ALA has been shown to improve insulin sensitivity in people with type 2 diabetes and may also be beneficial for people with prediabetes. In a meta-analysis of seven randomized controlled trials, ALA was found to significantly reduce fasting blood glucose and hemoglobin A1c (a measure of long-term blood sugar control) in people with type 2 diabetes (Ziegler et al., 1999).
May reduce oxidative stress: ALA is a potent antioxidant that can help reduce oxidative stress in the body, which may have a number of beneficial effects on health. In a review of the research, ALA was found to significantly reduce markers of oxidative stress in people with diabetes and other conditions (Packer et al., 1995).
May improve nerve function: ALA has been shown to improve nerve function in people with diabetes-related nerve damage (neuropathy). In a meta-analysis of seven randomized controlled trials, ALA was found to significantly improve nerve conduction velocity (a measure of nerve function) and reduce neuropathic symptoms such as pain, burning, and tingling in people with diabetic neuropathy (Ziegler et al., 1999).
May improve cognitive function: Some research suggests that ALA may have a positive effect on cognitive function, although more research is needed to confirm this. In a study of older adults with age-related memory decline, daily supplementation with blueberries (which contain ALA) was found to significantly improve memory (Krikorian et al., 2010).
May have anti-inflammatory effects: ALA may have anti-inflammatory effects, which may be beneficial for a number of health conditions. In a review of the research, ALA was found to significantly reduce markers of inflammation in people with diabetes and other conditions (Kontush et al., 2002).
May have anti-aging effects: Some research suggests that ALA may have anti-aging effects, although more research is needed to confirm this.
Overall, while there is still much that is not known about the potential benefits of ALA, it appears to be a promising supplement with a number of potential health benefits. As with any supplement, it is important to speak with a healthcare provider before starting to use ALA.
References:
Kontush A, Spranger T, Reichhold S, et al. Alpha-lipoic acid as a new therapeutic option in atherosclerosis: a review. Curr Drug Targets Cardiovasc Haematol Disord. 2002;2(1):29-37.
Krikorian R, Nash TA, Shidler MD, et al. Blueberry supplementation improves memory in older adults. J Agric Food Chem. 2010;58(7):3996-4000.
Packer L, Witt EH, Tritschler HJ. Alpha-lipo
]]>A question that is often asked: is 4000 IU a high dose? The answer is yes and no.
As far as the dose of vitamin D3 is concerned available as a supplement it is very high because most general practitioner doctors only describe a dose of 400IU (Ie i/10) of our dose and market places like Amazon restrict us from selling any higher dose for fear of going over the normally recommended NHS limits.
In some countries for example in India they are so much higher doses over the counter where you can buy doses of 20,000 IU or above. This sounds totally ridiculous. However when you consider how much vitamin D3 is produced by sunlight you too might think that the dose is in fact reasonable, but maybe could be considerably higher especially if we answer the following question:
How much vitamin D3 is generated by one hour of sunlight?
The amount of vitamin D that is produced in the skin as a result of sun exposure can vary based on skin type. People with darker skin generally have higher levels of melanin, which is a pigment that helps to protect the skin from the harmful effects of the sun. Melanin absorbs UV radiation and reduces the amount of vitamin D that is produced in the skin. As a result, people with darker skin may require longer periods of sun exposure to produce the same amount of vitamin D as people with lighter skin.
According to one study, it is estimated that people with lighter skin (skin type I or II) may produce between 10,000 and 25,000 IU of vitamin D3 after one hour of sun exposure on the face, arms, and legs during the summer months (when the sun is highest in the sky). People with darker skin (skin type III to VI) may produce significantly less vitamin D under the same conditions.
It is important to note that these estimates are approximate and can vary widely depending on the specific circumstances. It is also important to be aware of the risks of overexposure to the sun, as excessive sun exposure can increase the risk of skin cancer.
Here is a reference for this information:
Can you combine Vitamin D3 capsules to achieve a higher dose?
Yes, however we always recommend taking guidance from your health professionals to assess your particular circumstances for example your skin colour, your ability to access sunlight (certain skin conditions may restrict this), whereabouts you live and the season.
Do you have to take vitamin D3 every day?
As Vitamin d3 is a fat soluble vitamin you actually don't have to take it every day but you can bunch it up for example taking two or three in a day and then skipping for a those three days (or accordingly to the number you took).
More references are avaialbel here:
Holick MF. Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. Am J Clin Nutr. 2004 Mar;79(3):362-71. [PMID: 14985560]
Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011 Jul;96(7):1911-30. [PMID: 21646368]
Webb AR, Kline L, Holick MF. Influence of season and latitude on the cutaneous synthesis of vitamin D3: exposure to winter sunlight in Boston and Edmonton will not promote vitamin D3 synthesis in human skin. J Clin Endocrinol Metab. 1988 Oct;67(4):373-8. [PMID: 3420491]
Holick MF. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr. 2004 Dec;80(6 Suppl):1678S-88S. [PMID: 15585788]
We use the following bacterial strains a high concentration
Bifidobacterium animalis, Bifidobacterium bifidum, Bifidobacterium longum, Lactobacillus acidophilus, Lactobacillus rhamnosus, and Streptococcus thermophilus are all types of bacteria that are found in the human gut microbiome. The gut microbiome refers to the community of microorganisms that live in the digestive tract and play a role in maintaining overall health.
Some potential benefits of these bacteria include:
Bifidobacterium animalis, Bifidobacterium bifidum, Bifidobacterium longum: These bacteria are commonly found in the human gut and are thought to have a number of potential health benefits. They may help to support the immune system, reduce the risk of certain infections, and improve digestive function. Some research has also suggested that these bacteria may have anti-inflammatory effects and may be beneficial for certain digestive disorders such as irritable bowel syndrome (IBS).
Lactobacillus acidophilus, Lactobacillus rhamnosus: These bacteria are also commonly found in the human gut and are thought to have a number of potential health benefits. They may help to support the immune system, reduce the risk of certain infections, and improve digestive function. Some research has also suggested that these bacteria may be beneficial for certain digestive disorders such as IBS and may help to reduce the severity of diarrhea.
Streptococcus thermophilus: This bacteria is commonly found in fermented dairy products such as yogurt and is thought to have a number of potential health benefits. It may help to support the immune system, reduce the risk of certain infections, and improve digestive function. Some research has also suggested that Streptococcus thermophilus may be beneficial for certain digestive disorders such as lactose intolerance.
(Note streptococcus may sound scary given that some varieties are detrimental to human health - however, not all types of streptococcus bacteria are harmful. Some types of streptococcus bacteria are found in the human gut microbiome and are thought to have potential health benefits.
We also include FOS Fiber
Fructooligosaccharides (FOS) are a type of dietary fiber that is made up of short chains of fructose molecules. FOS is a prebiotic, which means that it serves as food for the beneficial bacteria in the gut microbiome. By providing nourishment for these bacteria, FOS may help to promote the growth of beneficial bacteria and support the overall health of the gut microbiome.
Some research has suggested that taking a combination of probiotics (live microorganisms that are similar to the beneficial microorganisms found in the human gut) and prebiotics may have additional benefits compared to taking probiotics alone. For example, a study published in the Journal of Nutrition in 2008 found that supplementing with a combination of probiotics and FOS improved digestive function and reduced the risk of certain infections in humans.
It is important to note that the research on the potential health benefits of these bacteria and FOS is ongoing.
Brain health and probiotics:
In recent years, there has been increasing interest in the potential role of the gut microbiome in the development and function of the brain and the nervous system. This area of research is known as "psychobiotics." Some studies have suggested that altering the gut microbiome with the use of probiotics may have effects on mental health and behavior.
For example, a review published in the journal Brain, Behavior, and Immunity in 2017 found that some studies have suggested that probiotics may have antidepressant and anxiolytic (anxiety-reducing) effects in humans. Other research has suggested that probiotics may be helpful for reducing stress and improving sleep quality.
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Our research team has put together a few thoughts - Please read and learn but remember that you should always seek advice from your own healthcare professional:
Pyrroloquinoline quinone (PQQ) is a small molecule that is found in some foods and is also available as a dietary supplement. It has been suggested that PQQ may have a range of potential health benefits, including antioxidant and neuroprotective effects. Some studies have also suggested that taking PQQ together with coenzyme Q10 (CoQ10) may enhance the benefits of both compounds.
One potential benefit of PQQ is its antioxidant activity. Antioxidants are substances that can help to protect cells from damage caused by harmful molecules known as free radicals. Free radicals are produced naturally as a byproduct of metabolism, but they can also be formed in response to environmental stressors such as exposure to pollution, UV radiation, and certain medications. Free radicals can damage DNA, proteins, and other cellular components, which can contribute to the development of chronic diseases such as cancer and heart disease. By neutralizing free radicals, antioxidants can help to reduce the risk of these diseases.
PQQ has been shown to have potent antioxidant activity in a number of studies, including in vitro and animal studies. It is thought to act by scavenging free radicals and by stimulating the production of other antioxidants within the body, such as superoxide dismutase (SOD) and glutathione.
In addition to its antioxidant activity, PQQ has also been suggested to have neuroprotective effects. Some research has suggested that PQQ may help to protect neurons (nerve cells) from damage, which could potentially be beneficial for conditions such as stroke, Parkinson's disease, and Alzheimer's disease. However, more research is needed to fully understand the mechanisms behind these effects and to determine whether PQQ is effective in humans.
There is also some evidence to suggest that taking PQQ together with CoQ10 may enhance the benefits of both compounds. CoQ10 is a compound that is involved in the production of energy within cells and is also an antioxidant. Some studies have shown that CoQ10 can help to reduce oxidative stress and improve heart function in people with heart conditions.
A few studies have suggested that taking PQQ and CoQ10 together may have a greater antioxidant effect than either compound alone. For example, a study published in the Journal of Nutrition in 2009 found that supplementing with a combination of PQQ and CoQ10 reduced oxidative stress and improved markers of heart health in rats. However, more research is needed to confirm these findings and to determine whether the combination of PQQ and CoQ10 has similar effects in humans.
In conclusion, PQQ is a small molecule that has been suggested to have antioxidant and neuroprotective effects. While more research is needed to fully understand the potential benefits of PQQ and to determine its safety and effectiveness in humans, some studies have suggested that taking PQQ together with CoQ10 may enhance the benefits of both compounds. It is important to note that dietary supplements are not intended to replace a balanced diet and should be used with careI. f you are considering taking PQQ or any other dietary supplement, it is important to speak with a healthcare professional to determine whether it is appropriate for you.
If you are interested in learning more about the research on PQQ and other dietary supplements, you can search for scientific articles on these topics using online databases such as PubMed, which is maintained by the National Institutes of Health. You can also speak with a healthcare professional or a qualified nutritionist for more information on the potential benefits of PQQ and other dietary supplements.
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In the 1980s, medication for migraines were developed. However, these medications can cause serious side effects. Moreover, some people are not able to take these drugs if they are at risk of medical conditions such as heart disease.
Nowadays, people want a more natural approach to preventing migraine headaches. Some vitamins and supplements may help in reducing migraine attacks, plus side effects are less likely. But, these vitamins and supplements are not instant treatments, it may take some time to be effective.
It’s also important to note that these natural treatments may not work for everyone. Some may also experience some mild side effects. Consult your health provider to find the right treatment for you.
Here are some vitamins and supplements that may help you with your migraine headaches:
Magnesium is a major mineral that maintains blood pressure, nerve, and muscle functions. Research has shown that people with recurring migraines have lower levels of magnesium than those who don’t have migraine attacks.
As a result, experts believe that magnesium plays an important role in treating and preventing migraines.
The British Association for the Study of Headaches recommends taking 400-600 mg of magnesium per day to prevent migraines. It’s best to take magnesium supplements for at least 3 months to find out if it works for you or not.
Here are some foods that are rich in magnesium:
Some side effects to take note of are diarrhoea, cramping, and nausea. This can mean you’re taking above the recommended dosage.
Vitamin B2 or riboflavin is responsible for converting food into fuel. It also helps metabolise protein and fats. People who suffer with migraines show a glitch in the metabolic process.
There are limited studies on why Vitamin B2 helps in preventing migraines, but it is noticeable that those who have Vitamin B2 deficiency are more prone to migraine.
Studies show that low levels of certain B vitamins, including vitamin B2, can lead to brain fog symptoms. Consuming vitamin B2 or riboflavin helps in guarding against brain fog and keeps the nervous system functioning properly.
A review of 9 studies showed that participants who took 400 mg of vitamin B2 for 3 months showed reduced pain, frequency, and duration associated with migraine headaches.
A cohort study of 1,385 elderly and middle-aged groups was conducted from January 2014 to December 2017. Studies showed that by increasing the intake of riboflavin the multi-dimensional cognitive function was improved.
Vitamin B2 can be found in foods such as:
The good news is that vitamin B2 does not have any serious side effects. But, it can make your urine colour orange—which is normal.
Health organisations recommend taking 400 mg of vitamin B2 daily to help prevent migraines.
Coenzyme Q10 is a substance found inside the body. Cells use this substance to produce the energy needed for maintenance and growth.
Compared to Vitamin B2, there is little evidence for the effectiveness of CoQ10 for migraines.
According to author Peter S. Sandor, “A lack of cell energy in the brain may be a cause of migraine, CoQ10 may give a boost to those cells and help prevent migraine.”
A small trial was conducted in 2019 on women with migraines. Participants who took 400 mg of CoQ10 per day for three months showed a decrease in the duration, frequency, and severity of migraine attacks.
Another study found that taking the addition of 100 mg of CoQ10 to your migraine medication daily reduced the severity of migraine attacks per month.
Researchers concluded that CoQ10 has a significant effect on reducing the frequency and duration of migraine.
Some common side effects include:
It is recommended to take between 100-200 mg of CoQ10 per day. It should be taken for at least 3 months to see if it works for you.
5-HTP is a supplement that is used as an alternative treatment for migraines and headaches. It is used by the body to produce serotonin which is an important substance for normal brain and nerve function. Serotonin has a significant role in emotional moods, sleep, inflammation, pain control, and other body functions.
Despite the limited research, several studies found that 5-HTP is an effective supplement to reduce the severity, frequency, and duration of migraine attacks.
In 2011, an experiment was conducted to two siblings with a rare type of migraine called hemiplegic migraine. The study concluded that 5-HTP improved their migraine symptoms.
It is recommended to take 200 to 600 mg of 5-HTP supplements daily for adults. For children, 20 mg per 10 pounds of their body weight is recommended.
5-HTP has several side effects including:
Some people prefer taking L-tryptophan. L-tryptophan is an essential amino acid that helps the body produce proteins and brain-signalling chemicals. Both 5-HTP and L-tryptophan are used to synthesise the pathway of serotonin or melatonin. Studies have shown that L-tryptophan is best in treating insomnia, depression, sleep disorders, and anxiety. Additionally, it plays an important role in cognition, behaviour, and mood. Many women also use this to ease mood swings caused by premenstrual syndrome.
Low levels of L-tryptophan have been linked to depression. However, there is limited research to back such claims.
But, which one is better? It really depends on what you’re looking for. 5-HTP synthesises serotonin more effectively and faster than L-tryptophan—making it a better option for improving mood.
If your main goal is to improve your overall well-being and sleep, you may consider taking L-tryptophan.
Vitamin D3 helps the body absorb calcium to maintain strong bones. Vitamin D2 is derived from plant sources, while vitamin D3 comes from animal sources. Experts are investigating the link between migraine and vitamin D deficiency. Low levels of vitamin D are also associated with dementia and Alzheimer’s disease.
Here are the best sources of vitamin D3:
In 2015, a study was conducted on people who had about 4 to 14 migraine attacks per month where vitamin D3 and simvastatin were combined. They saw a reduction in the number of migraines per month. Those who took the placebo had one more migraine headache per month, on average.
In another study, a group of 12 males and 36 females with migraine ages 18 to 65 years were randomly assigned to take either vitamin D3 or placebo for 24 weeks. From the 4-week baseline to 24 weeks, supplementation of vitamin D3 showed a reduction in the number of migraine frequency compared to placebo. There were, however, no differences in pressure pain thresholds, migraine severity, or temporal summation.
Bromelain is a type of natural enzyme that helps break down protein. It can be found in the stem and fruit of a pineapple. It is also sold as a dietary supplement. Bromelain helps ease certain kinds of headaches, especially those from sinus infection or inflammation. People use bromelain to ease pain, muscle soreness, kidney stones, burns, and many other conditions. However, there is no scientific evidence that supports such claims.
According to Dr. Russell H. Greenfield, bromelain acts as an anti-inflammatory and helps reduce swelling. If being used to relieve sinus pain or headache, he recommends taking 200 mg of bromelain twice daily.
Bromelain helps reduce sinus pain by thinning the accumulated mucus—allowing it to train properly. Several studies have shown that taking bromelain together with antibiotics or antihistamine will help in rapidly reducing nasal swelling.
Due to its anti-inflammatory properties, bromelain may also help ease migraine headaches, tensions, and allergies.
N-acetyl cysteine or NAC is a form of amino acid L-cysteine. It has been used for decades to treat psychological disorders, lung conditions, and to improve athletic performance. Doctors believe that NAC helps in stimulating the synthesis of glutathione—a compound that helps fight free radicals that can cause damage and inflammation. Taking glutathione supplements does not adequately restore GSH levels in the brain because it cannot penetrate the blood-brain barrier.
NAC is also commonly used to treat cough, dry eye, flu, and many other conditions. It also boosts dopamine levels, reduces anxiety and depression, improves memory and mood, and clears up brain fog.
In a study conducted by the University of Notre Dame Australia, it was suggested that migraine can be caused by the inflammation of the brain’s coverings and the release of free radicals. 90 participants were asked to take NAC 600 mg, vitamin C, and vitamin E for 3 months. By the end of the trial period, the subjects reported a 30% decrease in migraine episodes per month.
When you have migraines, you know how these pulsing and throbbing headaches can impact your daily activities. While medications can help you manage migraines, you might experience side effects. That’s the reason why some people find “natural” supplements to find relief.
The good news, these supplements have evidence that they may help in migraine prevention.
If you’ve been taking a certain supplement and haven’t seen any improvement, you may be lacking other important supplements that work synergistically to help improve or prevent migraine headaches.
We recommend taking the following:
Disclaimer
Information provided by this article and our company is not a substitute for direct, individual medical treatment or advice. It is the responsibility of you and your healthcare providers to make all decisions regarding your health.
Why choose MigraSoothe by Bespoke Biotics?
MigraSoothe-B, MigraSoothe + Herbs, and MigraSoothe-Pro have been exclusively developed by Bespoke Biotics using their unique formulation.
If you’ve been experiencing frequent migraine attacks, you might be wondering which type of migraine you are experiencing. Some experience severe nausea with vomiting while others find it difficult to speak when having migraine attacks. Most migraine sufferers may experience cognitive symptoms, visual symptoms, depression, and anxiety. Some will even experience all of the symptoms together. That being said, migraine symptoms vary from person to person.
If you’re trying to research which type of migraine you have, you probably notice that there’s a long list of migraine types. In reality, there are only two main migraine categories—Migraine with Aura and Migraine Without Aura.
In this article, we will discuss the three main subtypes under Migraine with Aura namely:
Now, let’s discuss these key types of migraine with aura.
A vestibular migraine causes repeated dizziness or also known as vertigo in people who have a history of migraine. Migraines are mostly characterised by throbbing or pounding headaches, but with vestibular migraine, you won’t always experience headaches during migraine attacks. The word “vestibular” refers to the inner ear, this controls your balance and hearing. People who experience vestibular migraines might feel like objects are moving around them.
There are different names for this type of migraine with aura. Your healthcare provider might also call it:
The symptoms for vestibular migraines can include any of the following:
Majority of people who have vestibular migraines do not have headaches and vestibular symptoms at the same time. Since there’s no imaging or blood tests that can detect it, the International Headache Society has given a criteria to help your healthcare provider diagnose the disorder.
It’s possible that you have vestibular migraine if you experience any of the following:
Doctors will usually order an MRI and check your hearing and balance to rule out vestibular migraine. The following conditions are similar to vestibular migraine:
To reduce the intensity and number of episodes, people with vestibular migraines need to have a regular meal and sleep schedule, managing stress, regular exercise, and avoiding migraine triggers.
The treatment for vestibular migraines are somewhat similar to other types of migraines. Since there is no specific medication for vestibular migraines, most healthcare providers will prescribe abortive medication that suppresses the vestibular system during an episode.
If you are experiencing frequent attacks, your healthcare provider can recommend one or more of the following medications:
Migraine with brainstem aura or MBA is a rare subtype of migraine with aura that begins in the brainstem. It was previously referred to as basilar artery migraine or basilar migraine.
This is usually accompanied by disorders of consciousness or symptoms like speaking and hearing difficulties, vertigo, and loss of muscle control. Most people with MBA sees lines or spots accompanied by abnormal flashes of lights.
Most people who have migraine attacks with brainstem aura experience vertigo. It’s described as rocking, spinning, or pitching forward. This usually lasts for several minutes up to an hour.
If the primary symptom of your migraine attack is vertigo that lasts for more than an hour or a few days, it’s often referred to as vestibular migraine.
Studies show that migraine with brainstem aura only affect 0.04% of the general population and 10% of people with migraine with aura. Most patients with MBA have a family history of migraine and research shows that women are more at risk of developing this type of migraine than men.
Just like any migraine, you’ll most likely experience the common symptoms of migraine with aura, such as:
Since the MBA begins in your brainstem, you may experience the following symptoms on one side or both sides of your body:
Even though migraine with brainstem aura has been around for half a century, the cause is still unknown and the diagnosis is even questioned at times. There are no specific tests to diagnose migraine with brainstem aura. Instead, your healthcare provider will rely on your medical history and physical exam to assess your ability to think clearly, reflexes, physical strength, nerve function, and vision.
In 2018, the International Headache Society published specific guidelines for diagnosing migraine with brainstem aura. Before diagnosing MBA, two episodes must occur that includes two or more of the following symptoms:
Also, some MBA symptoms can be serious conditions such as epilepsy, brain tumour, store, poor blood flow to the brain, and congenital defects. To rule out other conditions, specific tests might be needed. These are some tests that your healthcare provider may recommend:
Dealing with MBA involves using medications and taking measures to prevent or reduce migraine attacks. The following medications are also used to treat other types of migraine headache symptoms which are also highly effective for migraine with brainstem aura.
Some migraine medications such as triptans are not recommended for preventing migraine with brainstem aura. Triptans constrict your brain’s blood vessels.
Here are some common abortive medications to reduce MBA symptoms:
Hemiplegic migraine is a rare and serious type of migraine wherein individuals will experience headaches accompanied by weakness on one side of the body. Typical migraine with aura symptoms such as changes in speech, sensation, and vision are also experienced. Motor weakness that are similar to stroke symptoms occur in hemiplegic migraines.
Here are some of the most common symptoms:
Here are some more severe symptoms to watch out for:
People with hemiplegic migraine may also experience neurological symptoms that last from one hour up to several days. But, most people resolve after 72 hours. Here are some symptoms:
Just like the previous subtypes of migraine with aura, your healthcare provider will examine you physically and family history. To be diagnosed with hemiplegic migraine, you need to have had at least two episodes. The individual must also have temporary symptoms including motor weakness, speech, vision, or senses.
Additionally, they should have at least two of the following:
Your healthcare provider needs to rule out potential serious conditions before diagnosing hemiplegic migraine. Some potential causes include stroke, seizure, and transient ischemic attack.
Having hemiplegic migraine can be distressing and scary. Proper diagnosis is needed to initiate the correct treatment to help manage and prevent attacks. Treatments for hemiplegic migraine involves preventive medications and pharmacological treatment. Individuals experiencing severe attacks may need hospitalisation and additional measures.
Patients can also be treated with the same preventive and abortive medications used for migraine with aura except for agents that may exacerbate ischemia. Here are some medications that may be used:
There are several supplements that can be helpful in helping with migraines.
Riboflavin or vitamin B2 keeps energy production run smoothly to help cells function and develop properly.It is also responsible for converting food into fuel. It also helps metabolise protein and fats. People who suffer with migraines show a glitch in the metabolic process. Riboflavin also helps in proper development of the skin, blood cells, lining of the digestive tract, and brain function.
However, the human body is not capable of producing riboflavin, it is a so-called essential vitamin. You can get vitamin B2 from dietary supplements or food.
Riboflavin deficiency people often have high levels of homocysteine and migraines. Although there are limited studies on why Vitamin B2 helps in preventing migraines, it is noticeable that those who have Vitamin B2 deficiency are more prone to having migraines.
An analysis of multiple studies showed that participants who took 400 mg of vitamin B2 for 3 months showed reduced pain, frequency, and duration associated with migraine headaches.
Vitamin B2 can be found in foods such as:
Coenzyme Q10 is a natural occurring substance found inside the human body. Cells use this substance to produce energy needed for maintenance and growth. It also helps in neutralizing harmful particles called free radicals—acting as an antioxidant.
CoQ10 deficiency is associated with different diseases such as cancer, Alzheimer’s, and heart disease.
There are several factors that can lower the levels of CoQ10 in the body including:
You can find CoQ10 in these foods:
According to author Peter S. Sandor, ““A lack of cell energy in the brain may be a cause of migraine, CoQ10 may give a boost to those cells and help prevent migraine.”
A small trial was conducted in 2019 on women with migraines. Participants who took 400 mg of CoQ10 per day for three months showed a decrease in the duration, frequency, and severity of migraine attacks.
Another study found that taking an addition of 100 mg of CoQ10 to your migraine medication daily reduced the severity of migraine attacks per month.
Researchers concluded that CoQ10 has a significant effect on reducing the frequency and duration of migraine.
Some common side effects include:
Bespoke Biotics offers Triple Strength CoQ10 300 mg with Vitamin B1. Suitable for vegans and vegetarians.
It is recommended to take 300 mg of CoQ10 with our Riboflavin 400 mg (Migrasoothe-B) daily to help prevent migraine attacks.
Adults should take 1 capsule daily after meals. Do not exceed the recommended daily dose.
Magnesium is an abundant mineral that maintains blood pressure, nerve, and muscle functions. It is also required in energy production, glycolysis, and oxidative phosphorylation. It is also involved in more than 600 processes in your body including:
Low levels of magnesium in the body is linked to several diseases such as clogged arteries, hereditary heart disease, high blood pressure, osteoporosis, stroke, and diabetes.
Research has shown that people with recurring migraines have lower levels of magnesium than those who don’t have migraine attacks. As a result, experts believe that magnesium plays an important role in treating and preventing migraines.
The British Association for the Study of Headaches recommends taking 400-600 mg of magnesium per day to prevent migraines. It’s best to take magnesium supplements for at least 3 months to find out if it works for you or not.
Here are some foods that are rich in magnesium:
Some side effects to take note of are diarrhoea, cramping, and nausea. This can mean you’re taking above the recommended dosage.
Bespoke Biotics offer a Mag-Shield PRO Magnesium Citrate 500 mg supplement which is easier and faster to absorb compared to other magnesium supplements. One 500 mg capsule provides 150 mg active magnesium in a highly bioavailable form.
Magnesium Citrate is one of the easiest forms of magnesium that the body can absorb so it is more effective than some higher dosed alternatives.
Adults can take 2-4 capsules per day.
To tackle migraine headaches of various descriptions magnesium should be combined with:
There are many other supplements which are also help but these are a formidable combination to start with. You can buy 60 days supply directly from Bespoke Biotics website. Simply take
Feverfew has been used for centuries to treat migraines and other health problems. It is believed to reduce inflammation in the blood vessels in the head and treat fever. People took feverfew to relive pains and aches in the first century.
Feverfew can be found worldwide and is prepared by drying the flowers, stems, and leaves.
In 2002, a study was conducted to migraine patients. Patients randomly took the feverfew in three doses (2.08 mg, 6.25 mg, 18.75 mg) three times per day for twelve weeks and compared it to the placebo group. Researchers found out that those who took 6.24 mg of feverfew three times a day is effective in reducing migraine headaches.
It can cause minor side effects such as bloating, contractions in pregnancy, gastrointestinal symptoms, nervousness, headache, dizziness, trouble sleeping, menstrual changes, joint stiffness, tiredness, pounding heart, rash, weight gain.
Ginger is a tropical plant and has been used in herbal medicines in China for more than 2,000 years.
The root of ginger has been used for numerous medical purposes including relieving stomach ailments, relieving nausea and migraine, arthritis, cold and flu symptoms, and neurological problems.
In 2014, a clinical trial was conducted involving 100 participants who had acute migraine. They were randomly treated with sumatriptan (a drug used to treat migraines) and ginger powder. Those who took ginger powder showed a significant decrease in headache severity in less than two hours. Additionally, they experienced less side effects than those who took sumatriptan.
Ginger can be taken in the form of capsules and tea. You can also mix a quarter teaspoon of ginger powder with a glass of water. Chewing ginger candy is also effective in relieving headaches and migraines.
Bespoke Biotics sell Migrasoothe + Herbs which contains Riboflavin + Feverfew + Ginger
Peppermint leaves and essential oils are used as a herbal medicine to relieve headaches, toothaches, spasms, nausea, and gastrointestinal problems. It is also used in foods and products such as toothpaste, cosmetics, and chewing gum. It grows throughout Europe and North America.
Peppermint oil and its active ingredient—menthol—is available in capsule form and teas. Menthol helps in relaxing the muscles and easing pain. Some people use it as a dietary supplement and essential oil applied directly to the skin.
In a 2010 study, experts found that menthol in a 10% solution was effective at relieving migraine pain and nausea when applied to the temples and forehead.
Although there are only limited studies about its clinical effectiveness, topical peppermint oil is a good herbal remedy to relieve migraine headaches. Peppermint oil has a cooling or tingling effect that can cause a numbing effect.
Peppermint oils are considered safe, but possible side effects include:
As there are limited studies on peppermint oils, it shouldn’t be applied to the chest of infants or children as it can cause serious side effects to children when inhaled.
Disclaimer
Information provided by this article and our company is not a substitute for direct, individual medical treatment or advice. It is the responsibility of you and your healthcare providers to make all decisions regarding your health.